According to the TMZ.com, her death was caused by a complication of diabetes.
Penny once played Myrna Turner in the sitcom series "The Odd Couple" and also played Laverne DeFazio in the series "Laverne & Shirley".
Her career as a director began when she directed "Big", starring Tom Hanks in 1988. At that time she was the first female director to earn more than $100 million.
After Penny Marshall passed away, many Hollywood celebrities pay tribute on social media:
Here are some popular movies that Penny Marshall has played and also directed:
Laverne & Shirley TV Series - Laverne DeFazio
Big (1988) - Director
Awakenings (1990) - Director